Casa Coco by Coco B Isla in Isla Mujeres.

Cancun, Mexico Cancun is one of the most popular destinations in the hemisphere, and while it may seem like it’s just because of megaresorts and spring breakers, there is far more to the destination than that. When you visit, you realize just how impressive the tourism infrastructure is, how broad the resort offering is, and how terrific the service can be. Cancun is really a hub to explore some of the vibrant destinations just a short drive away, from the mangrove-filled beauty of Mayakoba to the fishing-village charm of Puerto Morelos. And if you don’t want to leave the city center, you can shack up in true luxury at hotspots like Le Blanc and the Ritz-Carlton, Cancun. Feeling more adventurous? Take the ferry to nearby Isla Mujeres and try some of its world-class boutique hotels like Casa Coco.